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. 2022 Apr 22;27(9):2718. doi: 10.3390/molecules27092718

Figure 1.

Figure 1

Effect of a 12-week supplementation of CP and CTP on the left-hind-leg thickness, grip strength, muscle weight, and gastrocnemius histopathology. (A) Left-hind-leg thickness. The quadriceps (quad), gastrocnemius, and tibialis anterior were sampled. Data are the mean ± SE. Significant differences between YC versus AC are indicated as follows: * p < 0.05, ** p < 0.01. Significant differences between CP versus AC are indicated as follows: & p < 0.05, and && p < 0.01. Significant differences between CTP versus AC are indicated as follows: $$ p < 0.01. Significant differences between CP versus CTP are indicated as follows: # p < 0.05, ## p < 0.01. (B) Grip strength (N/g body weight). (C) Muscle tissue weight (g/100 g body weight). (D) H&E and Sirius red stained transverse-sections of gastrocnemius muscle and fiber cross-sectional area. Scale bar = 60 µm. (E) Quadriceps triglyceride, quadriceps total cholesterol, and fatty acid. Data are presented as the mean ± SE. Significant differences are indicated as follows: * p < 0.05, and ** p < 0.01. YC, young mice control (12 weeks old, n = 6); AC, aging control (60 weeks old, n = 6); CP, collagen peptide (60 weeks old, n = 6); CTP, collagen tripeptide (60 weeks old, n = 6).