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. 2022 Mar 30;23(6):772–780. doi: 10.1111/mpp.13195

FIGURE 3.

FIGURE 3

Plant TIR dimerization interfaces and higher oligomer formation. (a) Crystal structure of the RUN1 TIR domain highlighting filament formation through continuation of alternating AE and DE interfaces. (b) Structure of RPP1 tetrameric resistosome highlighting the TIR tetramer including two symmetrical AE dimerization interfaces and two asymmetric interfaces as NADase catalytic sites