Figure 3.

Graphene oxide (GO) coating on a collagen scaffold enhances alveolar bone regeneration. (A) Immunohistochemical assessment of subcutaneous tissue with scaffold implantation. ED1 and ED2 indicate macrophages, P4HB indicates fibroblasts, and ASMA indicates blood vessels, in red. I (B) Peroxidase staining of subcutaneous tissue implanted with scaffold. Arrows and double arrows indicate peroxidase-positive granulocytes and the implanted scaffold, respectively. (C) Photographs and radiographic images immediately and 2 weeks after the implantation of the GO scaffold (D) Histological assessments of new bone formation in the extraction socket at 2 weeks after scaffold implantation; arrows indicate residual GO. *, p < 0.05. [123] Copyright 2016, the Author(s).