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. 2022 May 2;19(9):5526. doi: 10.3390/ijerph19095526

Table 1.

Data Extraction of Selected Studies.

Author Study Technique Sample Interventions Outcome Follow-Up Results Jadad
Tsao J.W. et al., 2016 [30] Case Report MT 1 single case brachial plexus avulsion 15 min daily, 5 days/week Pain and Sensation 1 month
8 months
MT coupled with nerve grafting may relieve phantom limb pain and restore sensation /
Rosen B. et al., 2005 [31] Case Series MT 3 cases following hand surgery Different timing, no more specified Pain, ROM,
Sensation
Different timing, no more specified MT can contribute to restore sensation, pain and ROM after surgery of the hand /
Selles R.W. et al., 2008 [32] Case Series MT 2 cases with peripheral nerve
Injury (neuroma)
3–5 times each day for 15 min Pain (VAS) Different timing MT can contribute to reducing pain in people with neuroma /
Altschuler E.L. et al., 2008 [33] Case Report MT 1 case with fractured wrist 2–3 time each week for 15 min of MT combined with electrical stimulation Active ROM After treatment
3 months
MT combined with other approaches can contribute to recovery active motion /
Guillot A. et al., 2009 [34] RCT MI 14 people with hand burns
9 EG, 5 CG
EG: five MI sessions combined with conventional therapy
CG: conventional therapy
ROM
Pain (VAS)
After 2-week period treatment MI contributes to a better motor recovery in term of ROM. Pain outcome were not reported caused heterogeneity of medication and timing 1/5
Paula M.H. et al., 2016 [35] RCT MT 20 people with peripheral nerve and tendons injuries
11 EG, 9 CG
EG: Duran Protocol for tendons combined with 30 min MT
CG: Duran Protocol combined with classic sensory re-education
Sensibility (Rosen Score, SWS)
Function (DASH)
After 3 and 6 months MT does not contribute to better outcome. None statistical significant differences were observed. 3/5
Yun D. et al. 2019 [36] RCT MT 30 people with mutilating injuries
15 EG, 15 CG
EG: conventional physical therapy combined with MT (30 min daily, 3 days a week for 4 weeks)
CG: conventional physical therapy
Muscle Elasticity (MytonPRO)
Pain (VAS)
Function (PRWE)
None MT combined with conventional physical therapy improves hand function and reduces pain 3/5
Hsu H. et al., 2019 [37] RCT MT 11 people with peripheral nerve injuries
6 EG, 5 CG
EG: touch-observation and task-based mirror therapy for 12 weeks
CG: classic sensory re-education combined with 40 min hand/physical therapy
Sensibility (SWS test, Static 2 point discrimination)
Dexterity (PPT, MMDT, Pinch-holding-up activity test)
After 3 months Touch-observed and task-based mirror therapy result in improvement of sensation and manual dexterity 3/5
Rostami H.R. et al., 2013 [38] RCT MT 23 people with orthopedic injuries
12 EG, 11 CG
EG: hand therapy combined (30 min) with MT 30 min daily, 5 days a week for 3 weeks
CG: hand therapy 30 min with other 30 min of functional tasks observing affected hand
ROM
Function (DASH)
After 3 weeks Mirror therapy contribute to better outcomes for both ROM and hand function in post-intervention. After 3 weeks improvement in hand function remain, while not significant improvement in ROM was observed. 3/5
Abolfazi M. et al., 2019 [39] RCT MT 40 people with different hand injuries (nerves, tendons soft tissue)
20 EG, 20 CG
EG: 30 min mirror therapy plus 45 conventional rehabilitation twice a week for 8 weeks
CG: 75 min conventional rehabilitation
ROM
Pain (McGill)
Function (DASH)
Strenght (Dynamometer)
Dexterity (MMDT)
After 12 weeks Mirror therapy combined with conventional hand therapy contribute in reducing pain and disability, and improving hand function and ROM in both short term and follow-up. This approach seems does not influence strength and grip. 1/5
Stenekes M.W. et al., 2009 [40] RCT MI 25 people with flexor tendons injuries
12 EG, 13 CG
EG: motor imagery during immobilization combined with protocol for tendons rehabilitation
CG: protocol for tendon rehabilitation
Kinematic analysis
Pain (VAS)
Function (MHQ)
ROM (Range of Motion Kit)
Grip strength and pinch strength (digital dynamometer)
After 12 weeks Motor imagery positively influences central aspects of hand function (ie, preparation time) during the rehabilitation after flexor tendon repair, while other hand function modalities appear to be unaffected 2/5

RCT: Randomized Control Trial; MI: Motor Imagery; MT: Mirror Therapy; EG: Experimental Group; CG: Control Group; ROM: Range of Motion; VAS: Visual Analog Scale; SWS: Semmes-Weinstein monofilament test; DASH: Disability of the Arm Shoulder and Hand; PRWE: PPT: Purdue Pegboard Test; MMDT: Minnesota Manual Dexterity Test; MHQ: Michigan Hand Outcomes Questionnaire.