Figure 7.

Exposure to certain PFAS led to an increase in ΔΨ_m while carboplatin treatment decreased ΔΨ_m. PFAS (green box) increased ΔΨ_m in (a) OVCAR-3 and (b) Caov-3 cells. PFAS mixtures (purple box) did not affect ΔΨ_m in (c) OVCAR-3, but increased ΔΨ_m in (d) Caov-3 cells. Treatment with carboplatin or CCCP (pink box) decreased ΔΨ_m in (e) OVCAR-3 and (f) Caov-3 cells (mean ± SD expressed as a percentage of the vehicle control (dashed line); n = 4 independent experiments in duplicate). Significant differences between exposure group versus vehicle control are denoted by * (p < 0.05).