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. 2022 May 5;23(9):5176. doi: 10.3390/ijms23095176

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ΔΨ_m increases in OVCAR-3 and Caov-3 cells exposed to PFAS or PFAS mixtures then treated with carboplatin. ΔΨ_m increased compared to the vehicle control in OVCAR-3 (blue box) and Caov-3 (red box) cells after exposure to (a,b) PFOA, (c,d) PFHpA, (e,f) PFPA, or (g,h) PFAS mixtures at nearly all carboplatin concentrations examined (mean ± SD expressed as a percentage of the vehicle control; n = 3 independent experiments in duplicate). Significant differences between treatment group versus vehicle control are denoted by * (p < 0.05).