Figure 4.

Locomotor exercise improves micturition reflex in continuous voiding recording. (A) In terminal awake cystometry, the representative tracing of a raw recording of continuous voiding from a rat in different groups. Each IVP trace (blue) was accompanied with simultaneous recording of EMG_EUS (green). Red asterisks, voiding. Micturition duration measured by time from initial pressure increase to voiding end. Green dashed lines (between two red dashed lines), latency of EUS bursting. Bar graphs, compared with SCI without exercise, exercise reduced voiding threshold (B), peak IVP (C), micturition duration (D), latency (E), and duration of EUS bursting (F). Time-stretched recordings within yellow boxes in each trace shown in the right panels. Each trace contains high-frequency oscillation of bladder contractions and bursting EUS activity during voiding. *: p < 0.05; **: p < 0.01; ***: p < 0.001.