Table 3.

Surgical results and recurrence/progression status of different invasiveness groups.

Variable	GTR			Recurrence/Progression
	n (%)	OR, 95% CI	p-Value	n (%)	HR, 95% CI	p-Value
Classification 1 grade
0	208 (98.1%)	1.000		8 (3.8%)	1.00
I	216 (87.4%)	0.163 [0.056–0.476]	0.001	62 (25.1%)	7.85 [4.91–12.53]	<0.001
II	151 (68.3%)	0.053 [0.019–0.148]	<0.001	87 (39.4%)	13.48 [8.99–20.20]	<0.001
III	102 (45.7%)	0.016 [0.006–0.045]	<0.001	134 (60.1%)	23.30 [16.69–32.52]	<0.001
Revised-Knosp grade
0	189 (96.9%)	1.000		11 (5.6%)	1.00
1	233 (88.9%)	0.162 [0.048–0.549]	0.003	53 (20.2%)	4.31 [2.64–7.05]	<0.001
2	92 (82.9%)	0.129 [0.036–0.467]	0.002	27 (24.3%)	5.27 [2.66–10.43]	<0.001
3A	115 (62.5%)	0.026 [0.008–0.085]	<0.001	85 (46.2%)	10.78 [7.18–16.16]	<0.001
3B	28 (43.1%)	0.012 [0.003–0.041]	<0.001	44 67.7%)	19.63 [9.70–39.71]	<0.001
4	20 (23.3%)	0.005 [0.001–0.016]	<0.001	71 (82.6%)	26.28 [15.25–45.27]	<0.001
Classification 2 grade
0	165 (97.6%)	1.000		4 (2.4%)	1.00
1	199 (91.3%)	0.254 [0.085–0.761]	0.014	31 (14.2%)	6.96 [3.59–13.52]	<0.001
2	177 (83.1%)	0.119 [0.042–0.342]	<0.001	66 (31.0%)	16.42 [10.28–26.23]	<0.001
3	116 (53.5%)	0.028 [0.010–0.078]	<0.001	119 (54.8%)	32.89 [23.09–46.86]	<0.001
4	20 (23.3%)	0.007 [0.002–0.022]	<0.001	71 (82.6%)	62.24 [36.10–107.29]	<0.001
Radiological Invasiveness
No	514 (90.5%)	1.000		91 (16.0%)	1.00
Yes	163 (48.7%)	0.100 [0.070–0.142]	<0.001	200 (59.7%)	5.11 [3.98–6.57]	<0.001
Surgical Invasiveness
No	394 (93.4%)	1.000		48 (11.4%)	1.00
Yes	283 (58.8%)	0.102 [0.066–0.155]	<0.001	243 (50.5%)	6.40 [5.09–8.06]	<0.001
Histological Invasiveness
No	290 (80.3%)	1.000		99 (27.4%)	1.00
Yes	387 (71.4%)	0.611 [0.444–0.841]	0.003	192 (35.4%)	1.44 [1.14–1.81]	0.003
Cavernous Sinus Invasion
No	503 (87.3%)	1.000		106 (18.4%)	1.00
Yes	174 (53.2%)	0.165 [0.119–0.229]	<0.001	185 (56.6%)	4.06 [3.16–5.22]	<0.001

GTR: Gross-Total Resection; OR: Odds Ratio; HR: Hazard Ratio; CI: Confidence Interval.