Figure 5.

Effect of CMRO6 on glucose uptake and insulin-related signaling pathways. (a) Glucose uptake was measured in differentiated adipocytes with a Promega glucose uptake-Glo assay kit. (b) Phosphorylation levels of insulin-stimulated signaling pathways (Akt, AS160, and TBC1D1) and adiponectin expression, which is related to glucose uptake, in response to insulin and CMRO6 treatment. Results are presented as the mean ± STD of three replicates. Different letters within the figure indicate significant differences (p < 0.05).