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RT-PCR analysis of the apoptosis-related genes Bax, Bcl-2 and caspase-3 in (A) Jurkat and (B) THP-1 cell lines after 24 h of treatment with compounds 4a and 4d. The expression levels of the target genes were normalized against β-actin expression and expressed as a fold change relative to the control samples. * p < 0.05 and ** p < 0.01 indicate a significant difference in comparison to the untreated control.
