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IC50 values of compounds 4a–n against Jurkat and THP-1 leukemia cells.
| Compound No. | Cell Lines and IC50 (µM) | |
|---|---|---|
| Jurkat | THP-1 | |
| 4a | 6.1 ± 0.19 | 6.5 ± 0.18 |
| 4b | 17.4 ± 0.28 | 16.7 ± 0.61 |
| 4c | - | - |
| 4d | 4.4 ± 0.2 | 4.2 ± 0.2 |
| 4e | - | - |
| 4f | 12.55 ± 0.63 | 11.9 ± 0.3 |
| 4g | - | - |
| 4h | 13.4 ± 0.15 | 9.75 ± 0.35 |
| 4i | 33.8 ± 1.5 | 8.37 ± 0.1 |
| 4j | - | - |
| 4k | - | - |
| 4l | - | - |
| 4m | - | - |
| 4n | - | - |
| Doxorubicin | 1.3 ± 0.01 | 1.1 ± 0.01 |
(-) Inactive. Values are represented as the average ± SD (n = 3).
