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. 2022 Apr 29;12:838060. doi: 10.3389/fcimb.2022.838060

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Copyright © 2022 Chen, Li, Xie, Chen, Xue, Wang, Ye, Wu, Yang, Zhao, Zhang, Ding and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genomic mining and validation of the antiphotoaging metabolites of lactic acid bacteria (LAB). (A) Genes involved in the NAD, NADP, and oxidative stress pathways in different LAB strains. The antiphotoaging potential is indicated as a node, with green representing high potential and orange representing low potential. The existence of a gene is shown in the squares, with blue representing the presence of the gene and yellow representing the absence of the gene. (B) HPLC quantification of nicotinamide (NAM) levels in the minimum nontoxic dilutions (MNTDs) of different LAB strains.