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. 2022 May 2;11(9):1236. doi: 10.3390/plants11091236

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Major events in the legal history of Cannabis. The first six decades of the 20th century encompassed the enactment of strict laws to regulate Cannabis use. Soon after, the relaxation of regulations started with The Netherlands’ decriminalization of Cannabis in 1976. The first country to legalize recreational use of Cannabis was Uruguay in 2013, followed by Canada five years later. In 2020, the United Nations (UN) reclassified Cannabis by removing it from its most strict schedule of narcotic drugs.