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. 2022 Apr 23;11(9):2364. doi: 10.3390/jcm11092364

Table 1.

Studies that have investigated the effect of PRRT on meningiomas.

Reference Type of Study Cohort Response PFS (Months) OS (Months) Adverse Events/Toxicity
Bartolomei et al. [6] prospective n = 29 stabilization n = 19 progression n = 10 6 (from end of PRRT) 40 white blood cells n = 18 renal n = 1
Hartrampf et al. [46] prospective n = 10 stabilization n = 7 progression n = 3 91.1 105 none
Kreissl et al. [47] prospective n = 10 stabilization n = 8 Partial remission n = 1 complete remission n = 1 - - none
Kertels et al. [48] retrospective n = 11 stabilization n = 6 no response n = 5 12 37 temporary leukopenia n = 53 thrombozytopenia n = 15 renal n = 3 liver n = 1
Seystahl et al. [50] retrospective n = 20 stabilization n = 10 progression n = 10 5.4 not reached lymphocytopenia 70%

PFS: progression-free survival. OS: overall survival. PFS and OS are given as mean values.