Table 2.
Demographics of patients with CTCs≥3/5 mL blood (n=136) and mCTC≥1/5 mL blood (n=120) used for analysis of PRL-3 and MMP9 expression and its association with clinicopathologic features.
PRL-3 and MMP9 expression in CTCs | P value | PRL-3 and MMP9 expression in MCTC | P value | |||
---|---|---|---|---|---|---|
Characteristics | Negative | Positive | Negative | Positive | ||
Gender | ||||||
Male | 23 | 61 | 0.415 | 16 | 61 | 0.548 |
Female | 11 | 41 | 7 | 36 | ||
Depth of invasion | ||||||
T1–T3 | 23 | 67 | 0.834 | 15 | 67 | 0.721 |
T4 | 11 | 35 | 8 | 30 | ||
Lymphatic metastasis | ||||||
No | 18 | 46 | 0.427 | 11 | 41 | 0.629 |
Yes | 16 | 56 | 12 | 56 | ||
Distant metastasis | ||||||
No | 29 | 72 | 0.089 | 21 | 67 | 0.030 |
Yes | 5 | 30 | 2 | 30 | ||
TNM stage | ||||||
I+II | 16 | 33 | 0.122 | 11 | 20 | 0.070 |
III+IV | 18 | 69 | 12 | 77 |