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. 2022 Apr 29;12:878639. doi: 10.3389/fonc.2022.878639

Table 2.

Demographics of patients with CTCs≥3/5 mL blood (n=136) and mCTC≥1/5 mL blood (n=120) used for analysis of PRL-3 and MMP9 expression and its association with clinicopathologic features.

PRL-3 and MMP9 expression in CTCs P value PRL-3 and MMP9 expression in MCTC P value
Characteristics Negative Positive Negative Positive
Gender
 Male 23 61 0.415 16 61 0.548
 Female 11 41 7 36
Depth of invasion
 T1–T3 23 67 0.834 15 67 0.721
 T4 11 35 8 30
Lymphatic metastasis
 No 18 46 0.427 11 41 0.629
 Yes 16 56 12 56
Distant metastasis
 No 29 72 0.089 21 67 0.030
 Yes 5 30 2 30
TNM stage
 I+II 16 33 0.122 11 20 0.070
 III+IV 18 69 12 77