TABLE 3.
Cluster pairs that were found to be associated with significant connectivity changes between both interventions, during the EAT paradigm.
Cluster size (mm3) | MNI coordinates of peak (x y z) | Anatomical region | Cluster size (mm3) | MNI coordinates of peak (x y z) | Anatomical region | T (probiotic—placebo) | FDR |
756 | −21 69 15 | Frontal pole | 1,134 | 57 24 21 | Caudal area 45 | −4.51 | 0.013 |
3,402 | 42 9 30 | Caudal ventrolateral area 6 | 1,107 | −18 −93 −6 | Occipital polar cortex | −4.18 | 0.027 |
756 | −21 69 15 | Frontal pole | 3,051 | 54 21 30 | Inferior frontal junction | −3.85 | 0.030 |
756 | −21 69 15 | Frontal pole | 1,107 | 51 30 21 | Inferior frontal sulcus | −3.46 | 0.047 |
945 | 51 −42 9 | Caudoposterior superior temporal sulcus | 594 | −48 −51 9 | Caudoposterior superior temporal sulcus | −3.98 | 0.044 |
BNA, Brainnetome atlas; EAT, emotional attention task; FDR, false discovery rate; MNI, Montreal Neurological Institute; ROI, region of interest. None of these sub-clusters was among the predefined ROIs. Four of those sub-cluster belonged to the same larger cluster spanning over several BNA regions (italic).