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. 2022 Apr 21;14(9):2070. doi: 10.3390/cancers14092070

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Transcriptomic analysis of induced core glioma stem cells. (A) Correlation matrix for three GBM-DC replicates and three ic-GSC lines based on gene expression profiles. (B) t-SNE plot of three GBM-DC replicates (blue), three ic-GSC lines (green), and a representative centroid of the c-GSC population (red) using gene expression profiles (C) Scatter plot of enriched pathways in representative ic-GSC and c-GSC populations and colored based on their biological network classification. GBM-DC replicates: GBM-DC1, GBM-DC2, and GBM-DC3; ic-GSC lines: ic-GSC#1, ic-GSC#3, and ic-GSC#7.