Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 29;23(9):4974. doi: 10.3390/ijms23094974

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

(a) shows glucagon (GLU)-(green) and nNOS-(red)-immuno-positive cells in the islet of Langerhans of rats of control and those with 12 h and 24 h of diabetes. There was no co-localization between glucagon and nNOS. nNOS-immunoreactive ganglion cell (arrow) and varicose nerve fibres (arrow head) were observed in the exocrine pancreas. Note the significant increase in the number of nNOS-containing nerve profiles after 12 and 24 h of diabetes. Scale bar = 10 μm. (b) shows morphometric analysis of glucagon-positive cells in the islet cells of the endocrine pancreas. There was a significant (*** p< 0.001) reduction in the number of nNOS-immunoreative cells in the islet of Langerhans compared to control. The number of glucagon-positive cells in the islets increased markedly (# p < 0.01) 24 h after the induction of diabetes, compared to the control (n = 6).