Figure 2.

The characteristics of PDCOs in terms of recapitulation of human cancer biology. Organoids derived directly from human tumor tissue have been shown to accurately recapitulate tumor physiology, genetic features, histological properties, and cancer heterogeneity. Specifically, drug responses of PDCOs can exactly reflect clinical outcomes of PDCO-matched cancer patients. As a result, PDCOs are a promising tool to evaluate anticancer drug efficacy studies in clinic. Figure was created using BioRender.com (accessed on 31 March 2022).