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. 2022 May 10;2(5):342–352. doi: 10.1158/2767-9764.CRC-21-0176

FIGURE 4.

FIGURE 4

Combinations of selinexor with various KRAS G12C inhibitors inhibit the ability of KRAS G12C–mutant cancer cells to form colonies. MiaPaCa-2 cells were plated in 6-well plates (500 cells per well) and treated with combinations of selinexor with MRTX1257 (A), MRTX849 (B), and AMG510 (C) at the indicated concentrations for 72 hours and colony formation assay was performed as described in Methods. Images of crystal violet-stained colonies were captured and NIH ImageJ 1.5Oi software was used to measure the number and size of colonies. Data is representative of three independent experiments.