Figure 2.

Recognition of a novel object was improved by Nano-PSO treatment in TBI mice. TBI mice treated or untreated were subjected to the novel object recognition task (NOR) at two weeks following TBI as described in the methods: (A) mice treated with Nano-PSO before TBI; and (B) mice treated with Nano-PSO post-TBI represent preference index of time spent exploring the new object compared to the familiar object. Statistical analysis by One-way ANOVA revealed that TBI animals had a deficit in visual memory compared to all other groups. (A: F (3, 33) = 25.390, p = 0.000 Fisher’s LSD post hoc, *** p < 0.001, n = 8–10), (B: F (1, 15) = 14.127, p = 0.00 Fisher’s LSD post hoc, ** p < 0.01, n = 7–10). NS = Not significant. Values are presented as mean ± SEM.