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. 2022 Apr 23;11(9):2371. doi: 10.3390/jcm11092371

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Forest plots for complement inhibition. (A) We observed statistically significantly lower systemic complement inhibition in patients with early to intermediate nonexudative AMD versus non-AMD controls (p = 0.03). (B) There was no statistically significant difference in systemic complement inhibition in patients with geographic atrophy versus non-AMD controls (p = 0.82). Blue diamonds denote the 95% confidence interval (CI); dashed tails denote the 95% prediction interval for this multi-level random-effects model.