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Viability of normal cells after treatment with compounds 1, 4, and 5 compared with untreated control cells (UT). Peripheral blood mononuclear cells (PBMCs) were isolated from the buffy coats of healthy adult volunteers (NPB 177, NPB 178, NPB 179) and treated for 48 h with 20 μM of compounds 1, 4, or 5. Cells that were negative for YO-PRO-1 iodide and 7-AAD were scored as viable. Error bars are ±SEM.
