Table 2.
Geometric means of serum concentrations of biomarkers studied in pancreatic cancer cases and control subjects in the Shanghai Cohort Study.
| Biomarkers * (µmol/L) | Controls, n = 258 Geometric Mean (95% CI) |
Cases, n = 129 Geometric Mean (95% CI) |
p a |
|---|---|---|---|
| Serine | 186.37 (182.98–189.80) |
179.01 (174.33–183.80) |
0.017 |
| Glycine | 363.05 (356.96–369.24) |
345.52 (337.18–354.00) |
0.002 |
| Cystathionine | 0.28 (0.27–0.30) |
0.29 (0.27–0.31) |
0.70 |
| Cysteine | 272.00 (268.45–275.60) |
273.15 (268.01–278.30) |
0.73 |
| Sarcosine | 1.98 (1.92–2.06) |
2.03 (1.93–2.14) |
0.49 |
a p-value to compare geometric means adjusted for age and gender, level of education (no formal schooling, primary school, and secondary school or above), body mass index (<18.5, 18.5–<23.0, ≥23.0 kg/m2), smoking status (never, former, and current smokers), number of alcoholic drinkers per week (continuous), history of diabetes (no, yes), serum cotinine concentration (nmol/L), serum pyridoxal 5′-phosphate concentration (nmol/L), estimated glomerular filtration rate ((mL/min/1.73 m2) and total methyl donors. * Mean serum concentrations. The significant findings are demonstrated in bold fonts.