Table 1.
Characteristics of patients according to mortality at day 60
| variable | Alive (n = 668) | Death (n = 114) | p -value |
|---|---|---|---|
| Age > 66 years (%) | 277 (41.5) | 101 (88.6) | 0.0001 |
| Female sex (%) | 278 (41.6) | 45 (39.5) | 0.668 |
| Co-morbidity (%) | |||
|
Hypertension Chronic heart disease Diabetes mellitus Chronic liver disease Chronic kidney disease Chronic obstructive pulmonary disease Hematological neoplasia Solid neoplasia Solid organ transplant |
268 (40.1) 142 (21.3) 122 (18.3) 27 (4) 69 (10.3) 128 (19.2) 37 (5.5) 91 (13.6) 16 (2.4) 14 (2.1) |
78 (68.4) 61 (53.5) 37 (32.5) 7 (6.1) 33 (28.9) 25 (21.9) 14 (12.3) 27 (23.7) 4 (3.5) 4 (3.5) |
0.0001 0.0001 0.001 0.319 0.0001 0.491 0.007 0.006 0.516 0.317 |
| DSOA ≤ 6a (%) | 298 (51.6) | 70 (71.4) | 0.0001 |
| SaO2 ≤ 94%b (%) | 266 (42) | 65 (58.6) | 0.001 |
| Creatinine > 1 mg/dLc (%) | 71 (10.7) | 42 (36.8) | 0.0001 |
| Lymphocyte count ≤ 800 × 109/L (%) | 317 (47.5) | 78 (68.4) | 0.0001 |
| C-reactive protein > 7 mg/dLd (%) | 269 (40.6) | 83 (72.8) | 0.0001 |
| Ferritin > 517 ng/mLe (%) | 235 (47.7) | 53 (63.9) | 0.006 |
| LDH > 293 U/Lf (%) | 283 (46.8) | 69 (67) | 0.0001 |
| d-dimer > 700 ng/mLf (%) | 251 (41.4) | 78 (76.5) | 0.0001 |
| Cycle threshold (%) | |||
|
≤ 20 21–25 > 25 |
72 (10.8) 146 (21.9) 450 (67.4) |
27 (23.7) 38 (33.3) 49 (43) |
0.0001 |
| Intensive care unit admission (%) | 103 (15.4) | 33 (28.9) | 0.0001 |
DSOA days from symptoms onset to admission, SaO2 oxygen saturation at ambient air
aMeasured in 676
bMeasured in 745
cMeasured in 780
dMeasured in 777
eMeasured in 576
fMeasured in 708