Table 4.
Associations between 10 adverse childhood experiences and the reoccurrence of illness (ROI) index, lifetime and recent suicidal behaviors (SBs), the phenome of affective disorders, and immune and growth factor (GF) profiles.
| Variables | ROI | Lifetime SB | Recent SB | Phenome | IRS | NIT | GF |
|---|---|---|---|---|---|---|---|
| Mental trauma | 0.466 *** | 0.388 ** | 0.342 * | 0.547 *** | 0.467 *** | 0.401 ** | 0.447 *** |
| Physical trauma | 0.422 ** | 0.432 ** | 0.319 * | 0.455 *** | 0.436 ** | 0.410 ** | 0.449 *** |
| Sexual abuse | 0.231 | 0.225 | 0.315 * | 0.347 * | −0.128 | −0.186 | −0.078 |
| Mental neglect | 0.646 *** | 0.569 *** | 0.574 *** | 0.609 *** | 0.464 *** | 0.462 *** | 0.403 ** |
| Physical neglect | 0.001 | −0.043 | 0.035 | −0.120 | −0.171 | −0.251 | −0.011 |
| Domestic violence | 0.369 ** | 0.394 ** | 0.407 ** | 0.321 * | 0.197 | 0.140 | 0.215 |
| Drug abuse family | −0.108 | −0.084 | −0.024 | −0.082 | −0.040 | −0.082 | 0.047 |
| Family history | 0.266 | 0.240 | 0.275 | 0.469 *** | 0.280 * | 0.261 | 0.266 |
| Losing a parent | 0.293 * | 0.263 | 0.313 * | 0.281 * | 0.019 | 0.001 | −0.022 |
| Criminal | −0.099 | −0.114 | −0.034 | −0.125 | −0.159 | −0.130 | −0.189 |
| ACE Domain1 | 0.633 *** | 0.589 *** | 0.582 *** | 0.294 *** | 0.413 ** | 0.337 * | 0.473 *** |
* p < 0.05; ** p < 0.01; *** p < 0.001. IRS: immune-inflammatory response system; NIT: neuroimmunotoxic; GF: growth factor profile.