| 4-HNE | 4-hydroxynonenal |
| ASMase | acid sphingomyelinase |
| ADH | alcohol dehydrogenase |
| AH | alcoholic hepatitis |
| AIM2 | absent in melanoma 2 |
| ALD | alcoholic liver disease |
| ALDH | acetaldehyde dehydrogenase |
| AMPK | 5′-AMP-activated protein kinase |
| ASC | adaptor apoptosis speck protein |
| ASH | alcoholic steatohepatitis |
| ATP | adenosine triphosphate |
| CAT | catalase |
| CerSs | ceramide synthase |
| CYP2E1 | cytochrome P450 2E1 |
| DAG | diacylglycerol |
| DAMPS | danger-associated molecular patterns |
| ER | endoplasmic reticulum |
| FA | fatty acid |
| GSDMD | gasdermin D |
| GSH | glutathione |
| GSH-Px | glutathione peroxidase |
| GSSG-Rx | glutathione reductase |
| HCC | hepatocellular carcinoma |
| HSC | hepatic stellate cells |
| IL-18 | interleukin-18 |
| IL-1β | interleukin-1β |
| IL-6 | interleukin-6 |
| IR | insulin resistance |
| KC | Kupffer cells |
| LPS | lipopolysaccharide |
| MAFLD | metabolic dysfunction-associated fatty liver disease |
| MAM | mitochondria-associated membranes |
| MCD | methionine/choline-deficient diet |
| MDA | malondialdehyde |
| mGSH | mitochondrial glutathione |
| miRNAs | microRNAs |
| MMP | mitochondria membrane potential |
| mt-DNA | mitochondrial DNA |
| mtROS | mitochondrial ROS |
| NADH/NAD+ | oxidized and reduced nicotinamide adenine dinucleotide ratio |
| NAFL | nonalcoholic fatty liver |
| NAFLD | nonalcoholic fatty liver disease |
| NASH | nonalcoholic steatohepatitis |
| NF-κB | nuclear factor kappa-light-chain-enhancer of activated B cells |
| NLRC4 | nucleotide-binding oligomerization domain-like receptors CARD domain-containing protein 4 |
| NLRP3 | nucleotide-binding oligomerization domain-like receptor protein 3 |
| ox-mtDNA | oxidized mitochondrial DNA |
| PAMPS | pathogen-associated molecular patterns |
| PKCδ | protein kinase Cδ |
| PPARα | peroxisome proliferator-activated receptor-α |
| ROS | reactive oxidative species |
| S1P | sphingosine-1-phosphate |
| S1PRs | sphingosine 1-phosphate receptors |
| S1PR4 | type 4 sphingosine-1-phosphate receptor |
| SM | sphingomyelin |
| SMases | sphingomyelinases |
| SMS1 | sphingomyelin synthase 1 |
| SOD | superoxide dismutase |
| SQSTM1/p62 | sequestosome-1 |
| SREBP1c | sterol regulatory element-binding protein 1c |
| T2DM | type 2 diabetes mellitus |
| TCA | tricarboxylic acid cycle |
| TLR | toll-like receptor |
| TNF-α | tumor necrosis factor alpha |
| TXNIP | thioredoxin-interacting protein |
| UPR | unfolded protein response |
| VDAC | voltage-dependent anion-selective channel |
| WD | Western diet |
| WHO | World Health Organization |