Figure 11.

Protein analysis of indicated proteins in the brain of Rett Syndrome patients and non-Rett Syndrome controls. (A) Western blot analysis of the indicated proteins in the post-mortem human brain tissues (frontal cerebrum) compared with controls. The NIH NeuroBioBank ID of the samples are provided below the Western blot images. For detailed information about these samples, please refer to Table 4. (B) Quantification of the indicated total proteins from A. n = 3, and data are reported as mean ± SEM. (C) Quantification of the indicated phosphorylated proteins from A, as well as the ratio analysis of the phosphorylated proteins from A versus their own non-phosphorylated pan proteins, *: p < 0.05, **: p < 0.01, ***: p < 0.001.