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The processes regulated by the PI3K/Akt pathway which are involved in the histologic evolution of acute myocardial infarction. Stage I—histologic changes and processes directly induced by ischemia, stage II—beginning of inflammatory process, stage III and post-infarct left ventricular remodeling—irreversible histologic changes in the myocardium such as collagen secretion. ECM—extracellular matrix, HF—heart failure.
