Table 1.

Dysregulation of miRNAs in Primary Biliary Cholangitis.

miRNAs	Tissue	Notes	Reference
miR-122a, miR-26a, miR-328, miR-299-5p	Liver	miR-122a/miR-26 DOWN miR-328/miR-299-5p UP	Padgett et al., 2009 [39]
miR-506	Liver	miR-506 UP	Banales et al., 2012 [34]
miR-15a-5p, miR-20a-5p, miR-140-3p, miR-106b-5p, miR-3654, miR-181a-5p	PBMCs	abnormal expression of 17 miRNAs that control cell differentiation and signal transduction	Qin et al., 2013 [40]
hsa-miR-505-5p, hsa-miR-141-3p, has-miR-26b-5p	Sera	hsa-miR-505-3p/miR-197-3p DOWN	Ninomiya et al., 2013 [41]
hsa-miR-122-5p, hsa-miR-141-3p, hsa-miR-26b-5p	Sera	disease biomarkers	Tan et al., 2014 [42]
miRNA-122, miRNA-378, miRNA-4311, miRNA-4714-3p	Sera	risk stratification	Sakamoto et al., 2016 [43]
miR-92a	Sera, PBMC	pathogenesis (Th17 cell differentiation)	Liang et al., 2016 [44]