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. 2022 May 3;18(5):e1010488. doi: 10.1371/journal.ppat.1010488

Fig 9. Glycan N450 reorientation leads to higher coverage of V5 in Z1800M D10 and D11.

Fig 9

Ensemble model using the wildtype T/F, D10, and D11 Env gp120 sequences shows the glycan at N450 (HXB2 N463) on the top (brown points) and a single conformation of the glycan on the bottom (brown sticks). (A, D) Z1800M T/F Env where the glycan is inserted below the loop, exposing V5 and (B, E) D10 and (C, F) D11 generations where the glycan is oriented on top of the protein surface, shielding V5. The V5 hypervariable loop is shown in red.