Table 3. Replication across ethnic subsamples in the HRS.

Phenotype	SNP name	Location	Minor allele	European ancestry(N)*	African ancestry(N)*	Hispanicancestry(N)*	Fixed effect p value†	Random effectp value‡	Fixed effect†:OR or beta	Random effect‡:OR or beta	Q §	I ¶
Grip strength decline	rs28665699	19200185	A	5228	–	409	0.00150	0.00150	−0.0418	−0.0418	0.3341	0.00
Gait speed decline	rs77608580	19196968	A	3319	381	237	0.00775	0.72900	0.0424	0.0146	0.0577	64.95

^*N: sample size by group included in the meta-analysis.

^†Fixed effect: p value and effect size.

^‡Random effect: p value and effect size.

^§Cochrane’s Q statistic: indicator of variance across sample effect sizes.

^¶I: heterogeneity index to quantify dispersion across samples.