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. 2022 May 16;132(10):e156125. doi: 10.1172/JCI156125

Figure 5. snoRNAs are upregulated in DM1 patients and are correlated with clinical outcomes.

Figure 5

(A) Violin plot of computed muscle snoRNAs score in CON, DM1-PRE, and DM1-POST. Correlation graphs and values of the muscle snoRNA score against metrics of (B) lean mass (TLM and appendicular skeletal muscle [ASM]), (C) function (6-MWT, 5XSTS, and TUG tests), and (D) strength (maximal knee extension, grip strength, and pinch grip). n = 10. *P < 0.05 versus CON, 1-way ANOVA followed by Bonferroni’s correction; #P < 0.05 versus DM1-PRE, 2-tailed paired t test corrected for multiple comparisons; $P < 0.05, linear regression analysis.