Table 5.
Patient Number | T-Cell Malignancy | T-cell treatment or PCD treatment first?* | First Line T-Cell Treatment | T-Cell Progression? | PCD | First Line PCD Treatment | PCD Progression After First Line Treatment? | PCD Clearance after T-Cell Treatment? |
---|---|---|---|---|---|---|---|---|
3 | T-LGLL | Only T-cell | MTX | Yes | Plasmacytosis | None | No | Undetermined* |
4 | PTCL | PCD | CHOEP | No | Plasmacytoma | IFRT | Yes | No |
5 | T-LGLL | T-cell | Cyclosporine | No | MM | Bortezomib/Lenalidomide/Dexamethasone | Yes | Yes |
11 | T-LGLL | T-cell | Methotrexate | No | MM | Cyclophosphamide/Dexamethasone | Yes | Yes |
13 | T-LGLL | PCD | Cyclophosphamide | No | MM | Bortezomib/Lenalidomide/Dexamethasone | No | No |
15 | T-LGLL | Only T-cell | Cyclophosphamide | Yes | MGUS | None | No | Yes |
18 | CTCL | Only PCD | None | No | MM | Daratumumab/Lenalidomide | Yes | No |
24 | CTCL | Only T-cell | Bexarotene/Extracorporeal Photopheresis | No | MGUS | None | No | Yes |
Frontline treatment information for patients that had clearance of their PCD cline and whether they received initial treatment for their T-Cell disease or PCD and whether they had progression to front line treatments.
*Exact start date for T-cell malignancy is unknown, but the patient was on Cyclosporine (Known T-LGLL treatment) at the time of PCD clone clearance.