Table 3.

Pattern electroretinogram (PERG), transient and steady state, examinations by period (pre and post): current topical therapy alone OR current topical therapy + CIT/HOMO one tablet a day.

	Current topical therapy alone		Current topical therapy + CIT/HOMO		95% CI	p-value
	Pre	Post	Pre	Post
Pattern electroretinogram (P-ERG) transient
Central
Amplitude Amp-p50 (μV)	2.6 ± 1.7	2.6 ± 1.9	2.6 ± 2	3.2 ± 7.4	0.7 (−0.75–2.12)	0.35
Latency Lat-p50 (msec)	59.1 ± 7.1	57.6 ± 7.5	59 ± 8.6	59.4 ± 7.7	2 (−0.31–4.32)	0.09
Amplitude Amp-n95 (μV)	0.9 ± 2.3	1.2 ± 2.3	1.1 ± 2.7	1.5 ± 1.8	0.2 (-0.68–0.71)	0.05
Latency Lat-n95 (msec)	105 ± 23.8	108.1 ± 22.6	105.5 ± 25.1	104.5 ± 22.8	−4.3 (−11.7–3)	0.25
Inferior
Amplitude Amp-p50 (μV)	1.3 ± 1.3	0.9 ± 1.1	1 ± 1.1	1.2 ± 1.6	0.5 (0.02–0.93)	0.04
Latency Lat-p50 (msec)	57.5 ± 7.7	58.5 ± 1	59.1 ± 11	59.9 ± 8.3	−1 (−5.2–3.2)	0.66
Amplitude Amp-n95 (μV)	0.6 ± 0.8	1 ± 1.1	1.1 ± 1.2	1.1 ± 1.6	0.6 (0.2–1)	0.002
Latency Lat-n95 (msec)	111. ± 12.6	109.2 ± 15.2	108.3 ± 11.7	111.4 ± 12.8	4.1 (-1.9–10)	0.18
Superior
Amplitude Amp-p50 (μV)	1.2 ± 1.3	0.9 ± 1.2	1 ± 1.7	1.3 ± 1.6	0.6 (0.2–1.1)	0.009
Latency Lat-p50 (msec)	59.2 ± 7.6	60.4 ± 6.3	60.7 ± 6.5	58.7 ± 7	−3.3 (-6–0.5)	0.01
Amplitude Amp-n95 (μV)	0.8 ± 1.1	1.1 ± 1.1	1.1 ± 1.7	1.2 ± 1.5	0.2 (−0.4–0.7)	0.55
Latency Lat-n95 (msec)	111.8 ± 14.1	108.5 ± 13	110.1 ± 15.7	113.2 ± 19	6.5 (−0.6–13.5)	0.07
PERG Steady state (Hz)
Central
Amplitude	1.5 ± 1.3	1.6 ± 1	1.8 ± 1.2	1.8 ± 1.4	−0.01 (-0.5–0.4)	0.96
Latency	115 ± 30	114.1 ± 29.2	113.6 ± 29.6	113.6 ± 29	0.9 (−1.8–3.5)	0.53
Inferior
Amplitude	1.1 ± 1	0.7 ± 0.8	0.9 ± 0.9	1 ± 1.8	0.4 (-0.5–1.3)	0.34
Latency	129.3 ± 10.2	126.5 ± 12.6	127.6 ± 12	130.2 ± 10.3	5.3 (−2.6–13.2)	0.19
Superior
Amplitude	0.9 ± 1.4	0.8 ± 0.9	1 ± 1.2	0.9 ± 1.6	−0.2 (−1.1–0.8)	0.74
Latency	129.3 ± 10.5	132 ± 11.9	132.3 ± 11.2	132.4 ± 10.1	−2.4 (−9.1–4.2)	0.47

P-values refer to the comparison between treatments, significant values are reported in bold (see text for statistical analyses methods).