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. 2022 May 14;15(6):689–702. doi: 10.1016/j.jiph.2022.05.003

Table 3.

Incidence and prevalence of venous thromboembolism in the outpatient population.

Author Design Population Thromboprophylaxis during Hospitalization Post discharge Thromboprophylaxis Indication for VTE Detection N D-Dimer, ng/mL Follow-up
Engelen[57] Prospective COVID-19 patients post discharge prophylactic or intermediate dose of LMWH (no description of dosages) 8% received prophylactic LMWH post discharge Screening US for all patients
CTPA or VQ screening for ICU patients or those with D-dimer ≥ 2 μg/mL
102 590 6 weeks post-hospital discharge
Patell[59] Retrospective Discharged patients with confirmed COVID-19 NR 13 patients received prophylactic dose anticoagulation (10 LMWH, 2 DOACs, 1 UFH); they were excluded from the analysis VTE diagnosis based on clinical suspicion 163 30 days
Roberts[58] Retrospective COVID-19 patients post-discharge Thromboprophylaxis during admission to all
Weight based dosing (<50 kg: enoxaparin 20 mg OD or 5000 units BID, 50–100 kg: 40 mg OD or 5000 units BID, 101–150 kg: 40 mg BID or 80 mg OD or UFH 5000 units TID, >150 kg: 60 mg BID or 120 mg OD or 5000 units TID)
None Testing for VTE was only done in symptomatic patients 1877 NR 6 weeks post-hospital discharge
Rashidi[60] Prospective Discharged patients with suspected or confirmed COVID-19 1490 (97%) received VTE prophylaxis (enoxaparin 40–60 mg/daily, UFH 5000 IU/QID) None VTE diagnosis based on clinical suspicion 1529 NR 45–55 days
Giannis[61] Prospective Discharged patients with confirmed COVID-19 82% of patients received VTE prophylaxis 12.7% received extended VTE prophylaxis with DOAC or LMWH (enoxaparin 40 mg SQ daily) for 30 days in patients with an IMPROVE VTE score of ≥ 4 or D-dimer ≥ 2X ULN. VTE diagnosis based on clinical suspicion 4906 340 ± 710 Up to 90 days post-discharge
Eswaran[62] Retrospective Discharged patients with confirmed COVID-19 NR 190 (42.5%) patients were discharged on VTE prophylaxis. VTE diagnosis based on clinical suspicion 447 30 days post-discharge