Table 1. Characteristics of the eight studies evaluated.

First author	Year	Study period	Design	Organ	Method	Patients, n	Age, mean	Male, n	Lesion, n	Size of lesion, mm, mean
Kitamura 12	2021	2006–2019	Retrospective	Stomach	PCM	20	72.1 ± 11.5	13	20	24.6 ± 11.6
					Non-PCM	46	72.7 ± 8.2	29	46	24.4 ± 13.2
Harada 15	2018	2017	Prospective	Stomach	PCM	48	75.6 ± 6.8	42	48	16.0 ± 6.6
					Non-PCM	48	75.2 ± 7.1	44	48	17.6 ± 11.3
Miura 3	2016	2006–2015	Retrospective	Duodenum	PCM	28	59.6 ± 10.9	16	28	30.5 ± 21.5
					Non-PCM	17	62.4 ± 12.7	12	17	21.0 ± 8.1
Kanamori 11	2017	2014–2016	Retrospective	Colorectum	PCM	47	67.5 ± 11.1	32	47	29.1 ± 11.0
					Non-PCM	49	69.7 ± 9.2	33	49	31.1 ± 9.4
Yoshida 10	2018	2006–2017	Retrospective	Colorectum	PCM	37	65.2 ± 13.5	18	37	31.1 ± 19.3
					Non-PCM	500	67.6 ± 10.6	282	500	37.3 ± 15.3
Takezawa 9	2019	2010–2017	Retrospective	Colon	PCM	266	67.0 ± 9.9	153	278	35.3 ± 13.7
					Non-PCM	248	67.0 ± 10.0	143	262	35.7 ± 16.2
Harada 14	2019	2017–2018	RCT	Colorectum	PCM	46	69.9 ± 10.4	29	46	26.4 ± 6.2
					Non-PCM	45	68.9 ± 14.1	26	45	26.8 ± 7.1
Yamashina 13	2020	2016–2018	RCT	Colorectum	PCM	59	69.3 ± 9.9	34	59	33.4 ± 11.7
					Non-PCM	55	67.8 ± 9.4	33	55	31.7 ± 11.5

PCM, pocket-creation method; CM, conventional method; RCT, randomized-controlled trial.