Table 3.
Group | Dose (mg/kg) | Body weight (g) | ||||
---|---|---|---|---|---|---|
Day 0 | Day 4 | Day 7 | Day 10 | Day 15 | ||
Normal saline | 0.3 ml | 23.90 ± 0.27 | 25.14 ± 0.19 | 26.10 ± 0.18 | 27.20 ± 0.12 | 28.15 ± 0.21 |
Diabetic control | 0.3 ml | 27.20 ± 0.44 | 27.80 ± 0.17 | 25.55 ± 0.40 | 25.15 ± 0.22 | 24.10 ± 0.50 |
Glibenclamide | 10 | 29.55 ± 0.22 | 30.25 ± 0.40 | 32.15 ± 0.25∗ | 33.65 ± 0.12∗∗ | 34.45 ± 0.10∗∗ |
Methanol extract | 200 | 26.10 ± 0.25 | 26.10 ± 0.21 | 29.95 ± 0.35 | 30.85 ± 0.35 | 32.45 ± 0.20∗ |
Methanol extract | 400 | 25.30 ± 0.15 | 26.25 ± 0.20 | 32.80 ± 0.14∗ | 32.25 ± 0.10∗ | 33.40 ± 0.45∗∗ |
Methanol extract | 500 | 26.24 ± 0.11 | 26.50 ± 0.36 | 32.95 ± 0.42∗ | 32.85 ± 0.27∗ | 33.95 ± 0.23∗∗ |
Results are expressed as mean ± SEM (n = 5), ∗P < 0.05, ∗∗P < 0.01, which considered significance compared with the control group (one-way ANOVA followed by Dunnett's test).