Table 7.
Group | Dose (mg/kg) | Total number of feces (mean ± SEM) | % inhibition of defecation | Total number of diarrheal feces (mean ± SEM) | % inhibition of diarrhea |
---|---|---|---|---|---|
Control | 1% Tween 80, 10 ml/kg | 8.25 ± 0.50 | — | 5.50 ± 0.27 | — |
Loperamide | 3 | 3.25 ± 0.23 | 60.61 | 2.25 ± 0.15 | 59.09 |
Methanol extract | 200 | 6.10 ± 0.31 | 26.06 | 4.90 ± 0.34 | 10.91 |
Methanol extract | 400 | 5.50 ± 0.15 | 33.33∗ | 3.80 ± 0.21 | 30.91∗ |
Methanol extract | 500 | 4.90 ± 0.27 | 40.61∗∗ | 2.95 ± 0.19 | 46.36∗∗ |
Results are expressed as mean ± SEM (n = 5), ∗P < 0.05, ∗∗P < 0.01, which considered significance compared with the control group (one-way ANOVA followed by Dunnett's test).