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. 2022 Jan 18;61(4):2129–2141. doi: 10.1007/s00394-021-02795-7

Table 2.

Cmax and Tmax for plasma DHA, EPA and EPA + DHA by treatment

Soup Extruded rice snack Gel capsule P valuea
Mean 95% CI Mean 95% CI Mean 95% CI
DHA Cmax (µg/mL) 52.4 [50.0, 54.9] 51.5 [49.1, 54.0] 55.2 [52.8, 57.6] 0.06
EPA Cmax (µg/mL) 18.5 [17.9, 19.1] 18.4 [17.8, 19.0] 18.6 [18.0, 19.2] 0.86
DHA + EPA Cmax (µg/mL) 70.5 [67.7, 73.3] 69.6 [66.8, 72.4] 73.5 [70.6, 76.3] 0.12
Median 25, 75 Percentile Median 25, 75 Percentile Median 25, 75 Percentile P valueb
DHA Tmax (hours) 4 [2, 8] 4 [2, 6] 6 [4, 6] 0.12
EPA Tmax (hours) 6 [2, 8] 6 [2, 8] 6 [4, 8] 0.50
DHA + EPA Tmax (hours) 4 [4, 8] 4 [2, 6] 6 [4, 6] 0.50

DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; Cmax, maximal concentration; Tmax, time to maximal concentration

aComparisons between treatments were performed using linear mixed effects models (n = 27) including treatment as fixed effect while controlling for ethnic and Time0 for the respective variable and treatment. Treatment*ethnicity and treatment*allocation order were not significant (P > 0.05)

bComparisons between treatments were performed using the non-parametric Friedman Test for related samples