Table 2.
Effects of PQQ on blood glucose concentrations and heart weight in mice with STZ-induced diabetes
| Groups | Ctl | DCMc | DCM + PQQLd | DCM + PQQMe | DCM + PQQHf |
|---|---|---|---|---|---|
| n = 10 | n = 10 | n = 10 | n = 10 | n = 10 | |
|
Blood glucose (mmol/L) |
6.73 ± 0.55 | 22.19 ± 4.34*** | 21.45 ± 4.33 | 19.66 ± 3.61 | 17.83 ± 2.28# |
| BW a(g) | 26.88 ± 1.37 | 23.16 ± 2.39*** | 22.77 ± 1.38 | 23.38 ± 2.61 | 23.81 ± 1.18 |
| HW/BW b(mg/g) | 4.06 ± 0.31 | 4.77 ± 0.54* | 4.18 ± 0.61 | 4.13 ± 0.38 | 3.70 ± 0.72### |
Data are presented as the mean ± SD
*P < 0.05
***P < 0.001 vs. Ctl
#P < 0.05
##P < 0.01
###P < 0.001 vs. DCM
aBW body weight
bHW/BW heart weight/body weight ratio
cDCM diabetic cardiomyopathy group
dDCM + PQQL diabetic mice treated with 10 mg/kg BW/day PQQ
eDCM + PQQM diabetic mice treated with 20 mg/kg BW/day PQQ
fDCM + PQQH diabetic mice treated with 40 mg/kg BW/day PQQ