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. 2022 Jan 8;61(4):1823–1836. doi: 10.1007/s00394-021-02768-w

Table 2.

Effects of PQQ on blood glucose concentrations and heart weight in mice with STZ-induced diabetes

Groups Ctl DCMc DCM + PQQLd DCM + PQQMe DCM + PQQHf
n = 10 n = 10 n = 10 n = 10 n = 10

Blood glucose

(mmol/L)

6.73 ± 0.55 22.19 ± 4.34*** 21.45 ± 4.33 19.66 ± 3.61 17.83 ± 2.28#
BW a(g) 26.88 ± 1.37 23.16 ± 2.39*** 22.77 ± 1.38 23.38 ± 2.61 23.81 ± 1.18
HW/BW b(mg/g) 4.06 ± 0.31 4.77 ± 0.54* 4.18 ± 0.61 4.13 ± 0.38 3.70 ± 0.72###

Data are presented as the mean ± SD

*P < 0.05

***P < 0.001 vs. Ctl

#P < 0.05

##P < 0.01

###P < 0.001 vs. DCM

aBW body weight

bHW/BW heart weight/body weight ratio

cDCM diabetic cardiomyopathy group

dDCM + PQQL diabetic mice treated with 10 mg/kg BW/day PQQ

eDCM + PQQM diabetic mice treated with 20 mg/kg BW/day PQQ

fDCM + PQQH diabetic mice treated with 40 mg/kg BW/day PQQ