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. 2022 Jan 19;33(6):1373–1384. doi: 10.1007/s00198-021-06263-0

Table 1.

Clinical features and diagnosis of 22 included patients with OI

Case number Gender Age at admission Family history Fractures Osteoporosis Skeletal deformity Short stature Blue/gray scleral hue Cardiovascular Diagnosis Mut type only prediction Add feature prediction
1 M 4 m Multiple Y Y L/S 1 1
2 F 16y Y Multiple Y Blue sclerae M/M 0 0
3 M 8 m Prenatal, multiple intrauterine fractures Blue sclerae L/S 0 0
4 M 1y4m 1 Y Blue sclerae M/M 0 0
5 M 4y4m 1 Y M/M 1 0
6 F 12y Y 1 Blue M/M 0 0
7 M 11 m Y 2 Y Y M/M NA NA
8 M 10y 2 Y Y L/S NA NA
9 M 2y6m Multiple Y M/M NA NA
10 M 5y7m Y 1 Y Blue sclerae M/M 0 0
11 M 18y Y Multiple Y Y L/S 1 1
12 M 8y Multiple Y Blue sclerae M/M 0 0
13 M 6y10m Y Multiple Y Blue sclerae M/M 0 0
14 M 11y Multiple Y M/M NA NA
15 M 11 m 1 Y Y PDA, PFO L/S 0 1
16 F 8y8m Y 3 Y Y M/M 1 0
17 M 9y9m 1 Y Y L/S 0 1
18 F 7y6m Y 1 Y Y Y Blue sclerae L/S 0 1
19 M 5 m Multiple Y Y L/S 0 1
20 M 8y Multiple Y Y L/S 0 1
21 M 4y Multiple Y M/M 1 1
22 F 6y10m Multiple  +  L/S NA NA

M/M mild/moderate, L/S lethal/severe