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. 2022 Jan 18;61(4):2143–2151. doi: 10.1007/s00394-022-02801-6

Fig. 3.

Fig. 3

Reduction in iodine status of German schoolchildren within about 1 decade: comparison between changes in DONALD study and changes in nationwide KiGGS study waves. A iodine concentrations; B 24-h iodine excretion rates (those for the KiGGS children were estimated from spot urine data); C estimated daily iodine intake (assuming fecal iodine losses of 10%) showing that about 50% of the urine samples of the 6–8-year-old children and ca. 45% of the 9–12-year-olds of KiGGS-2 translate into daily iodine intakes below the respective estimated average requirement (EAR). Iodine excretions of DONALD children with more than one urine collection within a respective age group were averaged before statistical analysis. All changes in both study types were highly significant (p < 0.0001, Wilcoxon rank sum tests)