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. 2022 May 13;13:2559. doi: 10.1038/s41467-022-30257-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b Single cell census of the WT and MYC-transformed VP (a) followed by unsupervised clustering revealed four luminal subsets (b VP; n = 1 per genotype). c, d Human MYC transcript (hg19MYC) is only observed in MYC-transformed VP and mostly restricted to the luminal subsets while murine Myc transcript (mm10Myc) is expressed across cellular populations and genotypes (c VP; n = 1 per genotype) and is not correlated with hg19MYC expression in luminal cells (d VP; n = 1 per genotype; edgeR: two-sided quasi-likelihood F-test).