TABLE 1.
Cochrane review | Study a | Reason(s) for exclusion | ||||
---|---|---|---|---|---|---|
Mean age <65 years | Secondary prevention of stroke | Sample size (n < 500) | Non‐English study | No stroke survival curve | ||
Garrison 16 2017 | JATOS 26 2008 | x | ||||
VALISH 27 2010 | x | |||||
Steurer 28 2016 | x | |||||
Musini 17 2019 |
Carter 29 1970 |
x | ||||
VA‐II 30 1970 | x | X | x | |||
HSCSG 31 1974 | x | x | ||||
ATTMH 32 1981 | x | |||||
Kuramoto 33 1981 | x | |||||
Sprackling 34 1981 | X | |||||
EWPHBPE 35 1989 | x | |||||
SHEP‐P 36 1989 | x | |||||
MRC‐TMH 37 1992 | x | |||||
HYVET P 38 2003 | x |
Abbreviations: ATTMH, Australian therapeutic trial in mild hypertension; EWPHBPE, European working party on high blood pressure in the elderly; HSCSG, hypertension‐stroke cooperative study group; HYVET P, hypertension in the very elderly trial pilot; JATOS, Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients; MRC‐TMH, medical research council trial of treatment of mild hypertension; n, number of participants; SHEP‐P, systolic hypertension in the elderly program pilot; VA‐II, Veterans administration cooperative study group on antihypertensive agents; VALISH, Valsartan in elderly isolated systolic hypertension.
Studies are listed chronologically.