Table 4.

FC Abnormalities in AUD as Predictors of Performance for Each Ataxia Test Condition

Multiple Regression	Eyes open			Eyes closed

Analyses 1-6	Stand	Walk	Balance	Stand	Walk	Balance
F value	2.02	3.87	3.66	2.33	2.51	1.27
p value	.027	.007	.01	.07	.05	.31
Effect size (R²) in %	49%	56%	55%	45%	47%	31%
Predictors	(t-Ratio) p	(t-Ratio) p	(t-Ratio) p	(t-Ratio) p	(t-Ratio) p	(t-Ratio) p
(+) MFG – MCC	(0.02) .98	(1.88) .074	(−0.47) .65	(−0.32) .76	(−0.43) .67	(−0.76) .46
(−) MFG – caudate	(−0.08) .94	(−2.68) .014	(−0.43) .67	(1.65) .12	(0.08) .94	(0.12) .90
(−) IFG – insula	(2.63) .016	(0.76) .46	(2.74) .012	(2.10) .049	(3.84) .001	(1.15) .26
(−) IFG – SMA	(−1.42) .17	(−4.14) .001	(−2.80) .011	(−2.11) .048	(−0.79) .44	(−1.80) .088
(+) Cereb. – precuneus	(−0.55) .59	(−2.37) .028	(−3.00) .007	(0.68) .50	(−0.37) .71	(−0.87) .39
(+) Cereb. – MFG	(−3.80) .001	(−2.72) .013	(−2.32) .031	(−0.88) .39	(−2.09) .05	(−1.80) .088
(−) ACC – MOG	(−0.80) .43	(0.62) .54	(−1.01) .32	(−0.69) .50	(−1.01) .33	(−0.30) .77

Note. FC aberration in AUD relative to CTL: (+) hyper-connectivity; (−) hypo-connectivity;

Abbreviations: MFG = middle frontal gyrus; MCC = middle cingulate cortex; IFG = inferior frontal gyrus; Cereb. = cerebellar ROIs; ACC = anterior cingulate cortex; MOG = middle occipital gyrus