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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Neurobiol Learn Mem. 2022 Mar 8;191:107609. doi: 10.1016/j.nlm.2022.107609

Figure 2.

Figure 2.

A: Timeline of experimental procedures for Experiment 1a. Rats first received two sessions of auditory fear conditioning in Context A, followed by a single exposure session to Context A. Then, rats underwent 6 sessions of either conditioned stimulus (tone) extinction in Context B, followed by an additional exposure session to Context A. Rats were then tested for fear to the tone in Context A and Context B. Grey shaded region represents CNO injections prior to behavioral testing. B: Post-shock freezing during the two conditioning sessions, followed by freezing during the first session of Context A exposure. Freezing to the tone during the 6 extinction sessions, followed by freezing during the second Context A exposure session. C: freezing to the tone in both Context B and Context A. CNO was injected 30 minutes prior to these sessions. “*” = significant difference (p < .05) between GFP and hM4Di in Context A. “#” = significant main effect of group collapsed across contexts (p < .05).