Table 1.
Patient/Age | 12 years old | 17 years old (+1 years of HSCT) |
18 years old (+2 years of HSCT) |
21 years old (+5.5 years of HSCT) |
---|---|---|---|---|
Complete Blood Count | ||||
ALC (cells/mm3) | 2700 | 1500 | 2600 | 2700 |
(normal range) | (1000–5300) | (1400–3300) | (1400–3300) | (1400–3300) |
Immunoglobulins | ||||
Ig A (g/dl) | 640 (67–433) | 341 (139–378) | 275 (139–378) | 318 (149–378) |
Ig G (g/dl) | 1720 (835–2094) | 1640 (913–1884) | 1300 (913–1884) | 930 (913–1884) |
Ig M (g/dl) | 218 (47–484) | 139 (88–322) | 120 (88–322) | 149 (88–332) |
Ig E (U/l) | 12,4 | |||
Lymphocyte subsets | ||||
CD3 (%) | 75 (60–76) | 77 (56–84) | 69 (56–84) | 70 (56–84) |
(cells/mm³) | 1125 (800–3500) | 1155 (1000–2200) | 1794 (1000–2200) | 1890 (1000–2200) |
CD4 (%) | 13 (31–47) | 23 (31–52) | 22 (31–52) | 31 (31–52) |
(cells/mm³) | 195 (400–2100) | 345 (530–1300) | 572 (530–1300) | 837 (530–1300) |
CD8 (%) | 58 (18–35) | 54 (18–35) | 48 (18–35) | 30 (18–35) |
(cells/mm³) | 870 (200–1200) | 810 (330–920) | 1248 (330–920) | 810 (330–920) |
CD19 (%) | 9 (13–27) | 15 (6–23) | 18 (6–23) | 15 (6–23) |
(cells/mm³) | 135 (200–600) | 225 (110–570) | 468 (110–570) | 405 (110–570) |
CD16 + 56 (%)* | 11 (4–17) | 6 (3–22) | 12 (3–22) | 13 (3–22) |
(cells/mm3) | 165 (70–1200) | 90 (70–480) | 312 (70–480) | 405 (70–480) |
CD45RA | 55 | |||
CD45RO | 51 | |||
TCR αβ | 62 | |||
TCR γδ | 17 |
Reference values are shown in paranthesis, abnormal values are indicated in bold.
HSCT hematopoeitic stem cell transplantation.
*Impaired NK-cell cytotoxicity was detected.