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. 2022 Jan 31;91(3):353–366. doi: 10.1002/ana.26303

FIGURE 3.

FIGURE 3

Adjacent seeds within and nearby tumor networks show distinct functional connectivity patterns. In 2 representative patients, PA12 and PA15, tumors and functional networks surrounding the tumors are highlighted. The anatomic boundaries of the tumors are demarcated by the blue lines. (A) Two pairs of seeds (pair A/B and C/D) are placed adjacent to the boundary of the tumor network in PA12. For each pair, one seed is placed in a functional network (seeds B and D) and another seed is placed nearby but within the tumor network (seeds A and C). (B) Seeds B and D demonstrate distributed connectivity corresponding to vATN and DMN, whereas seeds A and C show mostly local connectivity constrained within the tumor. (C) In the other patient with a tumor (PA15), 2 pairs of seeds (pair E/F and G/H) are placed within (seeds E and G) and nearby (seeds F and H) the tumor networks. (D) Similar to PA12, each pair of seeds shows distinct connectivity patterns. DMN = default mode network; FC = functional connectivity; vATN = ventral attention network.