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. 2022 May 13;15:60. doi: 10.1186/s13045-022-01267-7

Fig. 1.

Fig. 1

Distribution of histopathologically confirmed extramedullary manifestations. For 38 out of 225 patients, biomaterial of the affected site was available for histopathological confirmation of extramedullary manifestations (EM). Most frequently, EM was found in the skin, central nervous system (CNS) and pleura. Three patients had two affected EM sites and one patient had three EM sites